2018 TBI Model System Collaborative: Characterization and Treatment of Chronic Pain after Moderate to Severe Traumatic Brain Injury

Principal Investigator(s): View help for Principal Investigator(s) Cynthia Harrison-Felix, Craig Hospital; Jeanne Hoffman, University of Washington; Risa Nakase-Richardson, James A Haley Veterans Hospital

Version: View help for Version V1

Version Title: View help for Version Title Initial Submission

Name	File Type	Size	Last Modified
ICPSR Archive			09/12/2024 11:28:AM

Project Citation:

Harrison-Felix, Cynthia, Hoffman, Jeanne, and Nakase-Richardson, Risa. 2018 TBI Model System Collaborative: Characterization and Treatment of Chronic Pain after Moderate to Severe Traumatic Brain Injury. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2025-01-03. https://doi.org/10.3886/E193506V1

Project Description

Summary: This is a multi-site, cross-sectional, observational study involving a total of 18 centers. Using the infrastructure of the TBIMS, this study will add new study measures at collaborative study sites and link this information with TBIMS Form I and II variables to address the study aims. Results from this study will provide a more detailed picture of the problem of chronic pain after TBI by examining the types of pain that occur after TBI, which may be multiple types of pain for a subset of individuals, as well as the frequency of comorbid conditions. Identifying extreme phenotypes, such as demographic, individual, and treatment factors associated with those who have chronic pain but have minimal interference compared to those who are significantly impacted by pain, will allow us to identify treatment targets (behavioral, cognitive, biological, and molecular) to advance a personalized medicine approach to treatment unlike any approach in TBI and chronic pain to date. Outcomes from this study will include educational materials on chronic pain and pain treatment to benefit patients, family members, clinicians, and policymakers. Data from this study will have a direct impact on clinical practice, informing future work, and promoting understanding of constituent factors in extreme phenotypes.

Funding Sources: United States Department of Health and Human Services. Administration for Community Living. National Institute on Disability, Independent Living, and Rehabilitation Research (90DPTB0017-05-00)

Scope of Project

Subject Terms: pain; traumatic brain injury

Time Period(s): 9/30/2018 – 9/29/2023

Data Type(s): clinical data; observational data; survey data

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Published Versions

V1 [2025-01-03]

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