Perceived social support-giving moderates the association between social relationships and interleukin-6 levels in blood

Principal Investigator(s): View help for Principal Investigator(s) Tao Jiang, Ohio State University; Syamil Yakin, Ohio State University; Jennifer Crocker, Ohio State University; Baldwin Way, Ohio State University

Version: View help for Version V6

Version Title: View help for Version Title BBI

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Project Citation:

Jiang, Tao, Yakin, Syamil, Crocker, Jennifer, and Way, Baldwin. Perceived social support-giving moderates the association between social relationships and interleukin-6 levels in blood. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2021-11-21. https://doi.org/10.3886/E134442V6

Project Description

Summary: This study aimed to examine whether perceived availability to give support to others moderates associations between social relationships and inflammation. The data from the longitudinal follow-up of the National Survey of Midlife Development in the U.S. (MIDUS 2) were used. Results showed that perceived availability to give support moderated the associations between IL-6 and indicators of positive social relationships, including social integration, perceived support from others, and positive relations with others. Indicators of positive social relationships were associated with lower IL-6 among individuals higher, but not lower, in perceived availability to give support. The moderating effects of giving support held after adjusting for socio-demographic and health-related covariates.

Scope of Project

Subject Terms: social support; inflammation; social relationships; social integration; perceived social support; giving support

Geographic Coverage: United States.

Time Period(s): 2004 – 2009

Collection Date(s): 2004 – 2009

Universe: English-speaking adults who reside in the United States.

Data Type(s): clinical data; survey data

Methodology

Sampling: This study used the data from the longitudinal follow-up of the National Survey of Midlife Development in the U.S. (MIDUS 2). The baseline sample of MIDUS 2 consisted of individuals from four subsamples, including a national random digit dialing sample, oversamples from five metropolitan areas, siblings of individuals from the random digit dialing sample, and a national random digit dialing sample of twin pairs.

Data Source: This study used the data from Midlife in the United States (MIDUS 2), 2004-2006, and Midlife in the United States (MIDUS 2): Biomarker Project, 2004-2009. These data are publicly available and can be found in the following websites. The two datasets were combined into one dataset, according to participants' Study ID number (variable M2ID), for analyses (N = 1054). The analysis scripts (SPSS syntax) for the current study are attached as separate files above.

Ryff, Carol, Almeida, David M., Ayanian, John, Carr, Deborah S., Cleary, Paul D., Coe, Christopher, … Williams, David. Midlife in the United States (MIDUS 2), 2004-2006. Inter-university Consortium for Political and Social Research [distributor], 2017-11-20. https://doi.org/10.3886/ICPSR04652.v7

Ryff, Carol D., Seeman, Teresa, and Weinstein, Maxine. Midlife in the United States (MIDUS 2): Biomarker Project, 2004-2009. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2019-03-27. https://doi.org/10.3886/ICPSR29282.v9

Scales: Documentations for the measures, variables, and scales used in the MIDUS 2 and MIDUS 2: Biomarker Project can be found on the following websites.

Unit(s) of Observation: Individual.

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