Project Description
Summary:
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The Life-course Experiences And Pregnancy (LEAP) study is a
retrospective cohort study of
reproductive and perinatal health among 977 women participating since
adolescence in an ongoing longitudinal study of eating, activity, and
weight-related health (Project EAT: Eating and Activity over Time). For
Project EAT, male and female
adolescents aged 11-18 were recruited during the 1998-1999 school year
from 31
public middle and high schools in the greater Minneapolis-St. Paul area
of
Minnesota. Participants were subsequently surveyed every 5 years, with
the most
recent Project EAT survey completed in 2014-2015 when participants were
aged 25-36. Project EAT surveys have collected data on a wide
range of measures including depressive symptoms, unhealthy weight
control
behaviors, binge eating, home food availability, physical activity, and
body
weight. In 2019, participants in Project EAT who identified as women
were recruited to complete the LEAP survey if they had responded to at
least two of the three most recent Project EAT surveys and resided in
the United States. The LEAP survey asked participants about their
reproductive histories, including whether they had ever attempted to get
pregnant, whether they had been pregnant, and how many of their
pregnancies resulted in a live birth. Women who reported having at least
one live birth were asked, for each birth reported: their age when they
gave birth; the gestation length of the pregnancy; any diagnosed
pregnancy complications; and their best estimates of what they weighed
just before the pregnancy and how much weight they gained during the
pregnancy. In addition, for their first live birth only, women were
asked about a range of psychosocial and behavioral characteristics
during the pregnancy, including their perceived ability to live on their
income, depressive symptoms, binge eating, and unhealthy weight control
behaviors, among others. Women who had never been pregnant were asked
if they had ever attempted to get pregnant and, if so, if they had
received a diagnosis of infertility and/or sought fertility treatment.
Self-reports of key pregnancy characteristics for each woman’s live
births were validated against medical record data in a validation
substudy (n=250). All participants who reported at least one live birth
on the LEAP survey (n=656) were invited to sign HIPAA Authorization and
medical records release forms authorizing the study team to request
their prenatal, delivery, and postpartum medical records for each of
their pregnancies. Data on pre-pregnancy weight, measured weights at
each prenatal visit, delivery weight, gestational age at delivery, and
diagnoses of pregnancy complications were abstracted from the data.
Funding Sources:
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United States Department of Health and Human Services. National Institutes of Health. Eunice Kennedy Shriver National Institute of Child Health and Human Development (5R01HD090053)
Scope of Project
Time Period(s):
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1998 – 2020 (The Project EAT cohort was recruited during the 1998-1999 school year. Project EAT surveys were conducted every 5 years, with the most recent being 2014-2015. LEAP collected data from July 2019-July 2020)
Collection Date(s):
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1998 – 2020 (The Project EAT cohort was recruited during the 1998-1999 school year. Project EAT surveys were conducted every 5 years, with the most recent being 2014-2015. LEAP collected data from July 2019-July 2020)
Universe:
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This cohort includes people identifying their sex as female who have
been participating since the 1998-1999 school year in a longitudinal
cohort study of eating, activity, and weight-related health.
Participants were originally recruited from 31 public middle and high
schools in the greater Minneapolis-St. Paul area of Minnesota and the
majority still reside in Minnesota.
Methodology
Response Rate:
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The response rate to the LEAP survey was 78% among those who had responded to two of the last three Project EAT surveys.
For
the validation substudy, the response rate to the medical records
request was 58%. Records were successfully obtained for 38% of the
cohort.
Sampling:
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The LEAP sample comprises female-identifying individuals participating
in an existing longitudinal cohort study. These participants were
originally recruited from 31 public middle and high schools in the
greater Minneapolis-St. Paul area of Minnesota.
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