Exploring the boundaries of post-retrieval extinction in healthy and anxious individuals

Principal Investigator(s):  View help for Principal Investigator(s) Maria Alexandra Kredlow, New York University

Version:  View help for Version V1

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Project Citation: 

Kredlow, Maria Alexandra. Exploring the boundaries of post-retrieval extinction in healthy and anxious individuals. Ann Arbor, MI: Inter-university Consortium for Political and Social Research [distributor], 2019-07-19. https://doi.org/10.3886/E110781V1

Project Description

Summary:  View help for Summary Over a dozen studies have examined the efficacy of post-retrieval extinction (PRE) in healthy adults in the fear conditioning laboratory, with a recent meta-analysis (Kredlow et al.., 2016) reporting an overall small-moderate effect on attenuating the return of fear compared to standard extinction. The current study was designed to extend PRE effects to a mixed sample of healthy and anxious individuals, explore potential moderators, and examine the benefit of PRE for a memory conditioned over multiple days. These data were also used to examine whether demographic factors predicted failure to condition and whether modifications to the unconditioned stimulus enhanced fear learning.
Funding Sources:  View help for Funding Sources National Institute of Mental Health (F31MH103969); Clara Mayo Memorial Research Fellowship from the Department of Psychological and Brain Sciences, Boston University (n/a)



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